4130 Steel is wonderful stuff...run thin wall, same strenght as DOM heavy wall less weight.
7500 Series aluminum alloys are awesome, same strength, same elongation, but massive price.
It all depends what you want to do and how much ya got!
Go crazy, do a Carbon fibre tub like an Indy car with titanium and aluminum mounting points.
Weight about the same as a popcorn fart, cost like a 3000 sq ft house with a view.
But it would be cool....
Zag