285x60R16 = 29.5" tall by 11.5 wide if I'm not mistaken. Considering how a 28.75x8.5 tire fits on mine (touches the frame, even with wider than stock backspacing), I would guess that they're gonna rub the frame REAL REAL bad if you don't get some serious wheel spacers. And then once you space the wheels out far enough to keep them off the frame, you might need to hammer/sawzall a bit in the front fenderwells.
Could probably be done, but not a 'quick and easy' thing to do, I would think.