the newer generation "superduty" trucks, arent ANYTHING even close to the older F-Superduty 1.5 ton trucks of the 80's/90's. the newer ones are just 1 ton pickups from what I'm aware of. the REAL F-Superduty didnt come with a pickup bed, it was mostly either box bodies, wreckers, or flatbeds and the like.
but even though you could dimensionally fit a sammy into the bed of one I'd imagine, why would you want to? well actually scratch that. my friend would get me to do it by betting wouldnt fit, and I'd just prove him wrong somehow. so yeah. I'm sure it CAN be done, but not hat it SHOULD be done