The 2227 code "Difference between intake manifold pressure and barometric pressure is larger than specification." Barometric pressure is observed by EVAP leak check module.
I have installed a '05 2.7 in my 93 Tracker and ran for a month without the newer vapor recovery canister, which caused the 2227 code. I have not noticed any change is gas mileage, performance or anything else. It has came back twice since then, once it may have been a loose fuel tank cap. It has not cleared on its own, so must need to be reset. I know of another swapped in motor that was running for months with the 2227 code, and may still be.
To me the issue was that if another more critical code came I would not be alerted because I already had the CEL.