A vehicle with almost a quarter million miles on it? If they can provide you all/most of or at least the the recent year's service records of what maintenance has been performed to it and when and you have driven it and maybe even had a mechanic you know and trust look it over and deem it in decent shape, then sure, go for it.
The reality is the vehicle probably will have little to no service/maintenance records with it. So even if you have a trusted mechanic look it over (and you should if you know little about vehicles) you need to accept the fact that you will be assuming a lot of maintenance/repair and replacement costs. Nothing lasts for ever, especially vehicles.
So... how much MORE are these 4 door vehicles with lesser miles around you? $1,000? $2,000? It doesn't take long before you can easily have that much money in required maintenance and repair costs. Even more if you don't perform the lion's share of the repair and maintenance costs yourself.
Personally, I'd opt for a 2 liter engine in a 4-door truck. The maintenance concerns would still be the same, however, major repairs relating to the engine will be a few hundred dollars less expensive on the 2 liter engine versus the 2.5 liter engine. The 2 liter engine is just as reliable when properly maintained and provides far better fuel economy for the duration of time you own it. The horsepower difference between the 2.5 liter V6 and the 2 liter 4 cylinder is negligible. The V6 produces about 19 more horse power than the 2 liter.
If you go into the purchase realizing you may have to replace normal wear items sooner rather than later, such as front control arms (bushings worn?), CV axles or CV boots, spark plugs, U-joints, rear wheel cylinders, brake pads and/or shoes, axle bearings or wheel bearings, maybe a brake line then go for it. I'm not saying all these items will fail all at once. I am saying if this truck is rolling on the original suspension components, or even the second set of suspension components, they are probably due to be changed and you should expect to have to replace them sooner than later, but not all at the same time necessarily.
Once you have caught up on needed maintenance and repairs, providing the engine is sound, it should serve you well for a few thousand miles. Many of us have bought used trucks, spent thousands of dollars on replacing normal wear items over a couple years... and now have a sound record on the mechanical condition of our trucks and we now pretty well know our truck and know when to expect to have to perform future repairs or maintenance on them.
Once you own one of these, you will hear the noise that shouldn't be there and pretty much know what to do about it. The largest maintenance issue with these trucks is just like any other vehicle, change the oil and filter regularly, use the correct oil and check the fluid levels regularly to know when to top them off.
There are a lot of these little trucks rolling around with over 200K miles on them. Mine has 205K right now. I would still hop in it and drive it anywhere. In fact, I do.
